Yibin Liu Successfully Defended Ph.D. Dissertation

Congratulations to Dr. Yibin Liu, M.S., Ph.D.! Yibin has successfully defended and passed her doctoral dissertation entitled “The Effects of Green Tea on Oxidative Stress and Working Memory” on May 11th, 2016 at Indiana University Bloomington. Dr. Liu has been offered a postdoctoral position in the Department of Nutrition Science at Purdue University. She will start her new role on June 1st. Congratulations to Dr. Liu on receiving her hard-earned doctoral degree and wish her continued success as she moves forward in her future careerYibin Defense

U.S. EPA 2015 Scientific and Technological Achievement Award Honorable Mention

The United States Environmental Protection Agency presents a 2015 Scientific and Technological Achievement Award (STAA) Honorable Mention to Dr. James Klaunig. The STAA program is among the most prestigious of the U.S. EPA’s scientific award programs that recognizes outstanding scientific and technological publications. Dr. Klaunig was recognized for his exceptional contribution to risk assessment activities. Congratulations on this Honorable Mention, Dr. Klaunig!

SOT 55th Annual Meeting Recap

Several members of the Klaunig Lab attended the Society of Toxicology’s 55th Annual Meeting and ToxExpo, which was held from March 13-17th, 2016 in New Orleans, Louisiana. The SOT meeting always promises stimulating talks, presentations on breakthroughs in the field of toxicology and educational and professional networking opportunities. The meeting was held at the Ernest N. Morial Convention Center in New Orleans, which was a terrific venue along the banks of the Mississippi River. In addition to attending the meeting, several students and faculty members participated in poster sessions and presentations.

Dr. James Klaunig gave a presentation titled, “Role of Endogenous Oxidative Stress in Understanding and Assessing MOA of Exogenous Exposure to Toxic Agents” during the workshop session, Bringing More Science into the Process of Risk Assessment for Endogenous Chemicals with Exogenous Exposures.

Dr. Zemin Wang presented a talk, “Mode of Action of Triclosan Induced Mouse Liver Tumors” during the platform session, Investigating Mode of Action in Chemical Carcinogenesis.

Yibin Liu presented a poster titled, “The Effect of Green Tea Extract on Working Memory in Healthy Women” during the Natural Products poster session.

Shawn SOT 2016

Shawn Li with his poster at the SOT meeting.

Shawn Li presented a poster titled, “Mode of Action of PFOA Induced Liver and Pancreatic Acinar Cell Tumors in Rats” during the Carcinogenesis II poster session.





Ben SOT 2016

Ben Elser with his poster at the SOT meeting.


Ben Elser, who won the 2016 Pfizer SOT Undergraduate Student Travel Award, presented a poster titled, “Mechanism of 1,3-Dichloropropene Induced Liver Tumors in Rat” during the Carcinogenesis II poster session, as well.






Additionally, Dr. Klaunig was a collaborator on two external posters, the first by Dr. Brian Hughes titled, “Evaluation of Chemically-Induced Choline Deficiency as the Mode of Action for Diethanolamine-Induced Mouse Liver Tumors” and the second by Dr. Aparajita Chowdhury titled, “The Effects of Polyhexamethylene Biguanide (PHMB) on Rat Liver”.
Overall, the SOT 55th Annual Meeting in New Orleans, Louisiana was a productive and enlightening experience for all in attendance. Members of the Klaunig Lab were enthusiastic about the connections that were made and the possibilities for future collaboration. We look forward to attending the next SOT 56th Annual Meeting in Baltimore, Maryland in 2017.


More information on the SOT Annual Meeting can be found on the SOT website.


Ben Elser Awarded 2016 Pfizer SOT Award

Recently, Ben Elser an undergraduate student in the Klaunig Lab won the 2016 Pfizer SOT Undergraduate Student Travel Award. According to the SOT website, the award was for undergraduates who are presenting a poster at the annual SOT meeting. The goal of the award is to foster interest in graduate studies in the field of toxicology. Approximately fifteen awards were given by Pfizer and those winners were selected based on the quality of the poster abstract submitted, personal statement, academic record and a supporting recommendation. Those recipients of the award will receive travel support, including lodging and complimentary meeting registration. Each recipient is paired with a Pfizer scientist who serves as a mentor for the SOT meeting and is recognized at a special breakfast hosted by Pfizer. The student is required to attend the SOT Undergraduate Education Program on Sunday and participates in other meeting activities.

More information on the SOT awards can be found on SOT website.

Dr. James E. Klaunig Elected President of Carcinogenesis Specialty Section

Professor James E Klaunig, Ph.D, ATS, IATP in environmental health has been elected president of the Carcinogenesis Specialty Section (CSS) of the Society of Toxicology (SOT) for the 2105-2016 year.  The Carcinogenesis Specialty Section founded in 1986 is a subgroup of the SOT that serves as a focal point for interaction of members interested in carcinogenesis. Section members have expertise and/or responsibilities in molecular mechanisms of carcinogenesis, genetic toxicology, testing strategies for carcinogens, chemoprevention and cancer risk assessment. The Section sponsors symposia, workshops and Section meetings at the Annual SOT meetings to provide opportunities for discussion of the latest developments in carcinogenesis. In addition, the Section sponsors Graduate Student Awards for meritorious research in carcinogenesis that is presented at the Annual SOT meeting. The objectives of the CSS include: Highlighting and presenting topical carcinogenesis research; Providing and exchanging educational materials and resources to the scientific community; Advising and updating regulatory agencies, the media, and the public worldwide on the latest and most relevant information on carcinogenesis; Providing a medium for sharing information on methods and recent applicable publications in carcinogenesis research;  Recognizing current and developing leaders in carcinogenesis research through awards and sponsored presentations.

More information about the Carcinogenesis Specialty Section of the SOT can be found on the CSS website.

SOT’s 54th Annual Meeting Recap

Drs. Klaunig, Wang and Wu recently attended the Society of Toxicology’s (SOT) 54th Annual Meeting from March 22-26, 2015 in San Diego, California. The SOT Annual Meeting provides researchers in the field of toxicology with ample opportunities to discuss their latest work as well as learn from leaders in the field. Additionally, the meeting allows for individuals to share original research from the past year.


Dr. Klaunig during his roundtable session.

Dr. Klaunig chaired and gave a sunrise continuing education session titled, “New Horizons in Chemical Carcinogenesis: Advances in MOA and Mechanism of Cancer Pathogenesis”. Additionally, he chaired a platform session “Investigating the MOA in Chemical Carcinogenesis” and chaired a roundtable session “The Future of Carcinogenicity Testing”.






Dr. Farombi, a former Visiting Scholar, and Dr. Wang during the poster session.

Dr. Wang and Dr. Wu each had a poster presentation during this meeting. Dr. Wang’s presentation was titled, “The Nuclear Receptor Constitutive Androstane Receptor (CAR) Is Essential for Toxaphene Induced Liver Tumorigenic Response in Mice”; Dr. Wu presented on “The Role of Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor in Dieldrin-induced Liver Tumors in Mouse”.




More information on the Society of Toxicology’s (SOT) 54th Annual Meeting can be found on the SOT website.

Dr. Zemin Wang Elected Councilor of AACT

Dr. Zemin Wang has been recently elected as Councilor of the American Association of Chinese in Toxicology (AACT) Specialty Section of the Society of Toxicology. He will serve this role for a two-year term starting May 1st, 2015, during the second year, he will also serve either as the Secretary or Treasurer. The AACT aims, include: “(1) to foster interactions among professionals of Chinese background and/or ethnicity in toxicological or related sciences through the exchange of information in education, technology, employment, or business opportunities; (2) to facilitate collaborative activities in toxicology-related research or projects between Chinese scientists or organizations in the US and abroad; (3) to promote the participation of scientists of any ethnical background who share the same common interests in toxicology and related fields” (AACT). This is an outstanding achievement for Dr. Wang. Congratulations!

More information on the American Association of Chinese in Toxicology (AACT) can be found on the AACT website.

Emerging Leaders in Nutrition Science Poster Competition Finalist – Yibin Liu

Congratulations to Ph.D. student, Yibin Liu, who has been chosen as a finalist for the American Society for Nutrition’s (ASN) Emerging Leaders in Nutrition Science Poster Competition. Yibin will prepare a poster for her abstract, Green Tea Consumption Reduces Oxidative DNA Damage and Lipid Peroxidation in Smokers and Non-Smokers. The competition was created to select the best research submitted by students and young researchers to ASN’s Scientific Sessions. All finalists will receive recognition in ASN meeting materials to promote this honor and the opportunity to attend a separate poster competition in Boston, MA.

More information about the American Society for Nutrition (ASN) can be found on the ASN website.

Rami Saadeh Publishes Paper on Children’s Development and Respiratory Toxicity

Rami Saadeh, a Ph.D. student in the Department of Environmental Health, recently published a paper in Environmental & Analytical Toxicology. The abstract of his review article entitled, “Child’s Development and Respiratory System Toxicity” can be found below.


“Contrary to the old saying, children are not small adults. Children are different from adults in their response to environmental stressors because of their special body composition, which continuously changes as they grow. Children’s development at each stage of their life needs special consideration, especially that harmful exposures might impact their normal development, and increases their susceptibility to diseases later in life. This paper reviews children’s biological characteristics, and their normal developmental changes that make them more susceptible to environmental exposures. The paper will also discuss ways in which this normal development is influenced by environmental toxicants especially early life exposures, as well as the possibility of disease development. In this review, asthma is used as an example of a respiratory disease influenced by environmental toxicants, and methods of risk assessment used to predict such a disease are discussed”.


The Hamner Institutes for Health Sciences PBPK Modeling Course

Rami Saadeh, a Ph.D. student in the Department of Environmental Health at IUB, recently attended a course on physiologically based pharmacokintetic (PBPK) modeling. The course was held at the Hamner Institutes of Health Sciences in Research Triangle Park in North Carolina from September 22-26, 2014.  It was a full week course, which covered the principles of PBPK modeling and the application of this technique in risk assessment, drug development, in vitro to in vivo extrapolation (IVIVE), and estimation of exposures from human biomonitoring data. The course featured comprehensive lectures and extensive hands-on computer modeling practice.

More information on the PBPK course and applications of PBPK modeling can be found on the Hamner Institutes for Health Sciences website.